Table 2. Characteristics of chromoblastomycosis cases in patients with chronic cutaneous and subcutaneous lesions, Madagascar, March 2013–June 2017*.
| Characteristic | Chromoblastomycosis |
Other,‡ n = 98 | p value | |||
|---|---|---|---|---|---|---|
| Severe,† n = 27 | Moderate,† n = 21 | NA, n = 2 | All, n = 50 | |||
| Period of recruitment | ||||||
| 2013, starting March 1 | NS | NS | NS | 6 (12.0) | 10 (10.2) | 0.12 |
| 2014 | NS | NS | NS | 6 (12.0) | 22 (22.4) | NS |
| 2015 | NS | NS | NS | 12 (24.0) | 35 (35.7) | NS |
| 2016 | NS | NS | NS | 17 (34.0) | 19 (19.5) | NS |
| 2017, through May 31 |
NS |
NS |
NS |
9 (18.0) |
12 (12.2) |
NS |
| Mean age, y, (SD) |
NS |
NS |
NS |
47.9 (15.7) |
37.5 (19.4) |
0.0005 |
| Age range, y | ||||||
| 3–17 | NS | NS | NS | 1 (2.0) | 16 (16.3) | 0.001 |
| 18–32 | NS | NS | NS | 5 (10.0) | 26 (26.5) | NS |
| 33–47 | NS | NS | NS | 21 (42.0) | 26 (26.5) | NS |
| 48–62 | NS | NS | NS | 10 (20.0) | 19 (19.4) | NS |
| 63–80 |
NS |
NS |
NS |
13 (26.0) |
11 (11.2) |
NS |
| Sex | ||||||
| M | NS | NS | NS | 46 (92.0) | 65 (66.3) | 0.001 |
| F |
NS |
NS |
NS |
4 (8.0) |
33 (33.7) |
NS |
| Occupation | NS | |||||
| Farmer | 17 (63.0) | 12 (57.1) | 2 (100.0) | 31 (62.0) | 45 (45.9) | 0.006 |
| Services sector | 7 (25.9) | 7 (33.3) | 0 | 14 (28.0) | 17 (17.4) | NS |
| Student | 1 (3.7) | 1 (4.8) | 0 | 2 (4.0) | 18 (18.4) | NS |
| Merchant-artisan | 1 (3.7) | 0 | 0 | 1 (2.0) | 13 (13.3) | NS |
| Unemployed |
1 (3.7) |
1 (4.8) |
0 |
2 (4.0) |
5 (5.1) |
NS |
| Anatomic location | ||||||
| Lower limb | 21 (77.8) | 17 (81.0) | 2 (100.0) | 40 (80.0) | 53 (54.1) | 0.005 |
| Upper limb | 3 (11.1) | 3 (14.3) | 0 | 6 (12.0) | 36 (37.7) | NS |
| Other§ |
3 (11.1) |
1 (4.7) |
0 |
4 (8.0) |
9 (9.2) |
NS |
| Duration of the lesion, y | ||||||
| <1 | 2 (7.4) | 1 (4.8) | 0 | 3 (6.0) | 56 (57.1) | <0.0001 |
| 1–2 | 1 (3.7) | 1 (4.8) | 0 | 2 (4.0) | 14 (14.3) | NS |
| >2 |
24 (88.9) |
19 (90.4) |
2 (100.0) |
45 (90.0) |
28 (28.6) |
NS |
| Clinical form | ||||||
| Nodular | 1 (3.7) | 3 (14.3) | 0 | 4 (8.0) | NS | NS |
| Verrucous | 1(3.7) | 4 (19.0) | 0 | 5 (10.0) | NS | NS |
| Tumorous | 5 (18.5) | 0 | 0 | 5 (10.0) | NS | NS |
| Cicatricial | 3 (11.1) | 1 (4.8) | 0 | 4 (8.0) | NS | NS |
| Plaque | 3 (11.1) | 7 (33.3) | 0 | 10 (20.0) | NS | NS |
| Mixed | 8 (29.6) | 3 (14.3) | 0 | 11 (22.0) | NS | NS |
| Mixed on the face |
2 (7.4) |
0 |
0 |
2 (4.0) |
NS |
NS |
| Modified by previous therapy | 4 (14.8) | 3 (14.3) | 0 | 7 (14.0) | NS | NS |
| NA | 0 | 0 | 2 (100.0) | 2 (4.0) | NS | NS |
*Values are no. (%) unless otherwise indicated. NA, not available; NS, not specified. †For definitions, see Table 1. ‡Sporotrichosis (n = 63) (12); mycetoma (n = 4); carcinoma, eczema, and cutanesous tuberculosis (n = 2); carpitis, erysipela, fibrosarcoma, cutaneous lymphoma, porokeratosis of Mibelli, prurigo nodularis, pyoderma, and papillomavirus (n = 1); not specified (n = 17). §Head and neck, thorax.