Table 3.
Outcomes Stratified by the Number of Identified Disease Components
| Outcome | Count of Identified Disease Components |
|||||
|---|---|---|---|---|---|---|
| 1 |
2 |
3 |
||||
| n/N (%) | OR (95% CI) | n/N (%) | OR (95% CI) | n/N (%) | OR (95% CI) | |
| Death, tracheostomy, or pulmonary vasodilator use at discharge | 9/20 (45) | Ref. | 24/30 (80) | 4.9 (1.4–17.2) | 21/23 (91) | 12.8 (2.4–70.0) |
| Individual components | ||||||
| Death before NICU discharge | 1/20 (5) | Ref. | 4/30 (13) | 2.9 (0.30–28.3) | 5/23 (22) | 5.3 (0.56–49.7) |
| Tracheostomy | 4/20 (20) | Ref. | 21/30 (70) | 9.3 (2.4–35.8) | 17/23 (74) | 11.3 (2.7–47.7) |
| Pulmonary vasodilator at NICU discharge* | 5/19 (26) | Ref. | 8/26 (31) | 1.2 (0.33–4.7) | 11/18 (61) | 4.4 (1.1–17.7) |
| Additional secondary outcomes | ||||||
| Home oxygen therapy* | 17/19 (89) | Ref. | 24/26 (92) | 1.4 (0.18–11.0) | 17/18 (94) | 2.0 (0.17–24.2) |
| Daily diuretic use at discharge* | 15/19 (79) | Ref. | 15/26 (58) | 0.36 (0.09–1.4) | 10/18 (56) | 0.33 (0.08–1.4) |
| Daily inhaled medication use at discharge* | 13/19 (68) | Ref. | 14/26 (54) | 0.54 (0.16–1.9) | 10/18 (56) | 0.58 (0.15–2.2) |
Definition of abbreviations: CI = confidence interval; NICU = neonatal ICU; OR = odds ratio; Ref. = reference.
n indicates the number of infants with the outcome and N indicates the total number of infants in each group.
*
Calculated for survivors to discharge.