Table 1.
Anthropometric parameters and clinical characteristics among subjects.
| All patients (n = 153) | Women (n = 76) | Men (n = 77) | P-values | |
|---|---|---|---|---|
| Age (years) | 54.0 (48.5–61.0) | 55.0 (52.0–60.8) | 52.0 (46.0–61.0) | NS |
| BMI (kg/m2) | 23.9 (22.7–25.8) | 23.7 (22.6–25.4) | 24.3 (23.1–26.0) | NS |
| WHR | 0.89 ± 0.06 | 0.86 ± 0.05 | 0.92 ± 0.05 | <0.001 |
| FBG (mmol/L) | 7.0 (5.9–8.0) | 7.1(6.1–8.0) | 6.9 (5.7–8.2) | NS |
| 2hPG (mmol/L) | 11.3 (8.3–14.7) | 11.2 (8.4–14.3) | 11.3 (7.9–15.3) | NS |
| HbA1c (%) | 7.6 (5.9–9.4) | 6.8 (5.9–8.5) | 8.1 (6.4–9.7) | 0.018 |
| HDL-c (mmol/L) | 1.3 ± 0.3 | 1.4 ± 0.3 | 1.2 ± 0.3 | <0.001 |
| LDL-c (mmol/L) | 3.0 ± 0.9 | 3.0 ± 0.8 | 3.0 ± 1.0 | NS |
| ALT (U/L) | 24.8 (17.9–36.4) | 21.8 (15.7–32.3) | 26.0 (20.9–38.9) | 0.024 |
| TBIL (μmol/L) | 13.3 (11.0–18.2) | 12.1 (9.9–15.9) | 15.4 (11.7–19.0) | 0.028 |
| BUN (mmol/L) | 5.3 (4.4–6.4) | 5.4 (4.4–6.5) | 5.3 (4.4–6.4) | NS |
| Cr (μmol/L) | 94.4 ± 17.5 | 87.7 ± 12.5 | 101.0 ± 19.0 | <0.001 |
| TG (mmol/L) | 1.7 (1.2–2.7) | 1.6 (1.1–2.2) | 2.0 (1.3–3.3) | 0.022 |
| TC (mmol/L) | 5.2 ± 1.1 | 5.2 ± 0.9 | 5.2 ± 1.2 | NS |
| 24hUALB (mg/24 h) | 55.7 (32.7–104.1) | 47.2 (25.9–87.8) | 70.4 (41.0–116.5) | 0.017 |
| FINS (μU/ml) | 14.0 (9.0–19.0) | 13.0 (9.0–21.0) | 14.0 (10.0–18.0) | NS |
| SBP (mmHg) | 120.0 (110.0–130.0) | 120.0 (105.0–135.0) | 120.0 (110.0–129.0) | NS |
| DBP (mmHg) | 75.0 (75.0–84.8) | 75.0 (70.0–80.0) | 80.0 (70.0–85.0) | NS |
| HOMA-IR | 4.6 (2.7–6.5) | 4.5 (2.7–6.9) | 4.6 (2.8–6.4) | NS |
| AIP | 2.1 (1.9–2.4) | 2.1 (1.8–2.2) | 2.2 (2.0–2.5) | 0.001 |
| Smoking, n (%) | 62 (40.5%) | 2 (2.6%) | 60 (77.9%) | <0.001 |
| Alcohol consumption, n (%) | 44 (28.8%) | 4 (5.3%) | 40 (51.9%) | <0.001 |
| Carotid IMT (mm) | 0.70 (0.60–0.80) | 0.67 (0.60–0.77) | 0.73 (0.64–0.80) | 0.003 |
| Femoral IMT(mm) | 0.73 (0.60–0.80) | 0.73 (0.60–0.80) | 0.73 (0.63–0.80) | NS |
| Iliac IMT (mm) | 0.79 (0.71–0.80) | 0.80 (0.70–0.80) | 0.77 (0.72–0.80) | NS |
| FGF19* (pg/ml) | 133.5 (81.6–219.2) | 147.8 (90.6–283.0) | 131.4 (76.4–193.5) | NS |
Log transformed before analysis. Data are means ± SD or IQR.
BMI, body mass index; WHR, waist/hip ratio; FBG, fasting blood glucose; 2hPG, 2-h post-prandial blood glucose; HbA1c, hemoglobin A1c; HDL-c, high-density lipoprotein cholesterol; LDL-c, low-density lipoprotein cholesterol; ALT, alanine transaminase; TBIL, total bilirubin; BUN, blood urea nitrogen; Cr, creatinine; TC, total cholesterol; TG, triglycerides; 24hUALB, 24-h urine microalbumin; FINS, fasting insulin; SBP, systolic blood pressure; DBP, diastolic blood pressure; HOMA-IR, homeostasis model assessment of insulin resistance; AIP, plasma atherosclerosis index; carotid IMT, carotid intima-media thickness; femoral IMT, femoral intima-media thickness; iliac IMT, iliac intima-media thickness; FGF19, fibroblast growth factor 19; SD, standard deviation; IQR, interquartile range.