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. Author manuscript; available in PMC: 2020 Dec 1.
Published in final edited form as: Psychoneuroendocrinology. 2019 Sep 18;110:104439. doi: 10.1016/j.psyneuen.2019.104439

Fig. 1.

Fig. 1.

Effects of adult onset DIO3-deficiency on body weight and the thyroid status.Timeline and overview of study (A). Genomic DNA recombination efficiency and remaining DIO3 activity in the olfactory bulb four months after tamoxifen (tam) or vehicle (oil) injection (B). Recombined vs intact mRNA allele expression ration in brain regions of experimental animals (C). Bodyweight was measured for two and a half month after injection (D). Serum T4 (E), T3 (F), and TSH (G) level of six month old mice Data are shown as mean±SEM with n=6–8 mice per experimental group. *, **, *** indicate P<0.05, P<0.01 and P<0.001 statistical differences, respectively, between genotypes (black asterisks) or sexes (red asterisks), as determined by Student’s t-test for each gender.