Table II.
Associations of adiposity in childhood with menstrual irregularity in adulthood in CDAH and BBS.
| Childhood adiposity | CDAH | BBS | ||||||
|---|---|---|---|---|---|---|---|---|
| Unadjusted model (n = 1010) | Model 1 (n = 1010) | Unadjusted model (n = 1238) | Model 1a (n = 1238) | |||||
| RR | 95% CI | RR | 95% CI | RR | 95% CI | RR | 95% CI | |
| BMI z-score | 1.11 | 0.94–1.31 | 1.13 | 0.96–1.34 | 1.09 | 1.00–1.18 | 1.09 | 1.00–1.19 |
| BMI category | ||||||||
| Normal | Ref. | — | Ref. | — | Ref. | — | Ref. | — |
| Overweight | 1.50 | 0.99–2.28 | 1.62 | 1.06–2.48 | 1.07 | 0.88–1.29 | 1.07 | 0.88–1.30 |
| Obese | 2.72 | 1.60–4.64 | 2.84 | 1.63–4.96 | 1.43 | 1.08–1.89 | 1.44 | 1.08–1.92 |
| WHtR, per 0.01 unitb | 1.03 | 1.00–1.06 | 1.03 | 0.99–1.06 | 1.03 | 1.00–1.06 | 1.03 | 0.99–1.06 |
| WHtR categoryb | ||||||||
| < 0.5 | Ref. | — | Ref. | — | Ref. | — | Ref. | — |
| ≥ 0.5 | 1.44 | 0.87–2.39 | 1.47 | 0.89–2.45 | 1.62 | 1.06–2.46 | 1.56 | 1.00–2.45 |
Model 1: adjust for childhood age, age at menarche, highest parental education and own-education
aModel 1 further adjust for race in the BBS
b n = 293 in BBS
RR, relative risk