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. Author manuscript; available in PMC: 2020 May 29.
Published in final edited form as: Kidney Int. 2019 Mar 28;96(3):642–655. doi: 10.1016/j.kint.2019.03.016

Figure 3 |. Glomerular RapGEF2 expression is lost in podocyte-specific RapGEF2 knockout (KO) mice.

Figure 3 |

(a) Immunostaining for RapGEF2 on kidney sections of control mice demonstrates widespread expression in both tubules and podocytes. Its podocyte expression is mainly cytoplasmic, where it co-localizes with the podocyte cytoplasmic marker nestin. Bar = low power, 50 μm; high power, 10 μm. (b) In podocyte-specific RapGEF2 KO mice, glomerular RapGEF2 expression is absent but tubular expression is preserved. Bar = low power, 50 μm; high power, 10 μm.