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. 2020 May 21;5(10):e136417. doi: 10.1172/jci.insight.136417

Figure 7. Summary of BAFF’s positive effects on anti-tumor immunity.

Figure 7

BAFF increases B cell antigen presenting activity, production of Th1 cytokines, and costimulatory molecule expression, leading to downstream Th1 activation and expansion, enhanced chemotaxis of proinflammatory cells via the CCR6-CCL20 axis, and enhanced Tc-mediated tumor lysis.