Fig 2. Obesity minimally alters cytokine production by peripheral blood CD4⁺ and CD8⁺ T cells in ccRCC subjects.

PBMCs obtained from ccRCC subjects (n = 18) and tumor-free controls (n = 19) were stimulated ex vivo and analyzed via intracellular flow cytometry for production of indicated cytokines by (A) CD4⁺ PMBCs and (B) CD8⁺ PBMCs. Data are presented as means ± SEM with individual values for each subject shown. Statistical analyses were performed using parametric one-way ANOVA or non-parametric Kruskal-Wallis test followed by Dunn’s multiple comparisons test. * p<0.05, ns = not statistically significant. Non-obese BMI<30, Obese BMI≥30.