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. 2020 May 29;15(5):e0228824. doi: 10.1371/journal.pone.0228824

Table 1. Definitions of the terminology used in the article, in accordance with OMERACT definitions [23].

Term Definition Examples
Core area An aspect of health or a health condition that needs to be measured to appropriately assess the effects of a health intervention. Core Areas are broad concepts consisting of a number of more specific concepts called domains. Pathophysiological manifestations, life impact, resource use/economic impact
Outcome domain An aspect of the effect of illness, categorized within the core area, but still relatively broad. Diarrhea, gastrointestinal symptoms, absenteeism, need for additional medical procedures.
Outcome Any identified result in a domain arising from exposure to a causal factor or a health intervention. Diarrhea incidence, number of school absence days, need for intravenous rehydration.
Outcome measurement instrument A tool chosen to assess the outcome. Visual stool form scale, symptom questionnaire, immunoassay tests for rotavirus detection.