Table 6. Birth weight outcomes by trial group and maternal and infant characteristics.
| Hospital-Measured Birth Weight, g (N = 315) | Study-Measured Birth Weight, g (N = 199) | |||||||
|---|---|---|---|---|---|---|---|---|
| Univariable Model | Multivariable Model | Univariable Model | Multivariable Model | |||||
| Unadjusted Difference, g (95% CI) | p-value | Adjusted Difference, g (95% CI) | p-value | Unadjusted Difference, g (95% CI) | p-value | Adjusted Difference, g (95% CI) | p-value | |
| Infant Characteristics | ||||||||
| RPC | reference | reference | reference | reference | ||||
| MG-T | -51 (-150, 47) | 0.31 | -44 (-154, 66) | 0.43 | -71 (-187, 45) | 0.23 | -17 (-142, 108) | 0.79 |
| PC-T | -60 (-161, 41) | 0.24 | -50 (-168, 68) | 0.41 | -83 (-204, 38) | 0.18 | -22 (-154, 109) | 0.74 |
| Female infant | -76 (-157, 6) | 0.07 | -74 (-157, 9) | 0.08 | -48 (-146, 50) | 0.34 | -56 (-152, 39) | 0.25 |
| Gestational age, (std.) | 59 (13, 103) | 0.01 | 48 (2, 94) | 0.04 | 126 (78, 174) | <0.001 | 129 (80, 179) | <0.001 |
| Maternal Characteristics | ||||||||
| Age, years | 9 (-5, 24) | 0.20 | 7 (-9, 23) | 0.37 | 6 (-11, 24) | 0.48 | -4 (-23, 14) | 0.66 |
| Height, (std.) | 47 (3, 90) | 0.03 | 42 (-4, 88) | 0.07 | 59 (9, 110) | 0.02 | 51 (-1, 104) | 0.05 |
| BMI < 18.5 | -20 (-113, 72) | 0.67 | -21 (-112, 71) | 0.66 | -10 (-122, 101) | 0.85 | -17 (-122, 89) | 0.75 |
| Baseline energy intake, (std.) | 3 (-42, 47) | 0.90 | 29 (-57, 114) | 0.51 | 50 (-3, 104) | 0.06 | 91 (-7, 188) | 0.07 |
| 32-week energy intake, (std.) | 7 (-46, 60) | 0.79 | -2 (-82, 79) | 0.96 | 31 (-22, 84) | 0.29 | 46 (-42, 134) | 0.30 |
| Baseline protein intake, (std.) | -9 (-53, 36) | 0.70 | -41 (-126, 44) | 0.35 | 23 (-29, 75) | 0.39 | -66 (-160, 28) | 0.17 |
| 32-week protein intake, (std.) | -1 (-53, 51) | 0.98 | -2 (-91, 88) | 0.97 | 6 (-46.5, 59) | 0.81 | -32 (-131, 67) | 0.52 |
| Farmer occupation | -12 (-110, 86) | 0.81 | 38 (-87, 162) | 0.55 | 2 (-109,113) | 0.97 | 19 (-113, 152) | 0.77 |
| Educational attainment | ||||||||
| < High school | reference | reference | reference | reference | ||||
| High school | 73 (-32, 177) | 0.17 | 58 (-54, 171) | 0.31 | 28 (-95, 151) | 0.65 | 37 (-92, 166) | 0.58 |
| Occupational school or above | 88 (-15, 192) | 0.09 | 107 (-29, 243) | 0.12 | 69 (-52, 190) | 0.26 | 123 (-26, 273) | 0.11 |
| Lives with family in-law | 35 (-55, 124) | 0.45 | 22 (-72, 117) | 0.64 | 63 (-44, 170) | 0.25 | 30 (-80, 140) | 0.59 |
Abbreviations: RPC = routine prenatal care; MG-T = food supplement from midgestation to term; PC-T = food supplement from preconception to term; BMI = body mass index; CI = confidence interval; std. = standardized: one unit corresponds to one standard deviation of the observed variable
Statistical significance (in bold) calculated under the Benjamini-Hochberg procedure to maintain an overall false discovery rate ≤5%.