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. 2020 Mar 27;12(5):736–749. doi: 10.1093/gbe/evaa064

Fig. 4.

Fig. 4.

—The influence of the negative effects of TEs (A) and transposition rates (B) on the minimum size of piRNA clusters. Each dot represents the outcome of a single simulation. The cluster size, the transposition rate, and the negative effect of TEs were randomly selected. To identify regions of the parameter space where piRNA clusters are not necessary to control TEs (nonwhite dots in the left panel), we show results for simulations performed without piRNA clusters. Dashed lines indicate the size of piRNA clusters in Drosophila melanogaster (3%). Large piRNA clusters with sizes of 0.1–1% are necessary to control TEs when transposition rates are high and negative effects of TEs are intermediate.