Fig 4. Oral iEP, needle-free and IM immunizations induce similar frequencies of B cell populations.

The frequency of activated memory B cells (A), resting memory B cells (B), tissue-like memory B cells (C) and naive B cells (D) was analyzed in the peripheral blood of iEP, needle-free and IM groups at weeks 0,1,4,5,16 and 17. Statistical significance was tested using repeated measures ANOVA with a Bonferroni post-hoc test. ** p≤ 0.01.