1. Gastrointestinal bleeding |
|
a. Esophageal varices, gastric varices, gastric vascular ectasia, etc |
[1, 3] |
b. Thrombocytopenia, coagulation disorder |
[2] |
2. Hemolysis |
|
a. Hypersplenism secondary to portal hypertension |
[5] |
b. Autoimmune hemolytic anemia associated with autoimmune hepatitis |
[6] |
c. Wilson’s disease with increased non-ceruloplasmin-bound copper |
[7] |
d. Zieve's syndrome, spur cell anemia |
[8, 9] |
3. Aplastic anemia associated with hepatitis |
[10] |
4. Alcohol |
|
a. Bone marrow toxicity |
[11] |
b. Malnutrition (e.g. folic acid deficiency, vitamin B12 deficiency) |
[11] |