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. 2020 May 29;15(5):e0232819. doi: 10.1371/journal.pone.0232819

Fig 5. TEM images of ultrastructural features of autophagy and apoptosis in the ovary of L. maximus.

Fig 5

(A) Normal primordial follicle with homogeneous chromatin in the nucleus and atretic follicle with altered morphology characterized by involuted nucleus, condensation of chromatin and numerous vesicles in the cytoplasm. (B) Detail of the normal primordial follicle cytoplasm containing a large amount of mitochondria (red dotted line) and few autolysosomes. (C) Detail of the altered oocyte with numerous autophagosomes and autolysosomes. (D) Apoptotic granulose cells from atretic follicles characterized by condensed nuclei, apoptotic bodies and (E) plasmatic membrane blebs (green arrow), autophagosomes, autolysosomes and lysosomes. N: nucleus, C: cytoplasm, M: mitochondria, AP: autophagosome, AL: autolysosome, L: lysosomes, PpF: primordial follicle, AtF: atretic follicle. GC: granulosa cell.