Table 2. Lead-SNPs of associated loci.
Cytoband | Lead SNP | Candidate | EA / OA | EAF | Info | associated CPBs | beta | SE | p-value | IA |
---|---|---|---|---|---|---|---|---|---|---|
Genes | ||||||||||
5q31.1 | rs201629990 | IL5 (78 kb) | GT / G | 0.038 | 0.982 | CPA_mean (A, M) CPA_max (A, M) | -0.401 | 0.068 | 5.22x10-9 | 6.85x10-3 |
6q21 | rs72942431 | SELL (trans-eQTL) | A / G | 0.300 | 0.940 | CPS_max (A) CPS_mean (A) | -0.151 | 0.029 | 5.36x10-8 | 0.466 |
4q22.3 | rs3821968 | BMPR1B (0 kb) | T / C | 0.118 | 0.961 | CPS_sum (A) | 0.299 | 0.057 | 1.91x10-7 | 0.840 |
20q13.31 | rs58056086 | TFAP2C (42 kb) | T / C | 0.088 | 0.887 | CPS_mean (W) CPS_max (W) | -0.319 | 0.061 | 2.21x10-7 | 2.60x10-4 |
19q13.33 | rs4539714 | FPR1 (989 kb) | C / T | 0.194 | 0.905 | CPA_sum (W) | 0.360 | 0.069 | 2.23x10-7 | 4.70x10-4 |
2p12 | rs6729048 | ABCC1 (trans eQTL) | A / T | 0.137 | 0.995 | CPA_sum (W) | -0.369 | 0.071 | 2.84x10-7 | 2.19x10-3 |
18q12.3 | rs7245281 | PSTPIP2 (160 kb) | A / G | 0.197 | 0.956 | CPS_sum (M) | -0.322 | 0.062 | 3.05x10-7 | 2.00x10-5 |