Table 6. Correlation of capillary and venous PQ plasma concentrations.
| Total (n = 205) | 24 hr post last dose (n = 150) | ≥ 7 days post dose (n = 55) | |
|---|---|---|---|
| Cven, ng/mL | 50.4 (0.504, 251) | 70.8 (9.67, 251) | 3.41 (0.504, 20.4) |
| Ccap, ng/mL | 56.3 (0.584, 292) | 73.5 (16.7, 292) | 2.84 (0.584, 22.6) |
| P value | <0.0001 | <0.0001 | 0.38 |
| Correlation equition: Ccap = a × Cven + b | |||
| a | 1.04 (0.978, 1.11) | 0.984 (0.886, 1.08) | 0.965 (0.828, 1.10) |
| b | 4.20 (-0.878, 9.27) | 10.6 (1.68, 19.5) | -0.182 (-1.02, 0.661) |
| R2 | 0.832 | 0.729 | 0.789 |
Concentrations represent medians (range) and correlation parameters represent means (95%CI).