Table 10. Trained parameter weights.
Parameters | Unweighted | Homozygous Trained | Heterozygous Trained |
---|---|---|---|
Stability (Stabilizing) | 1.0 | -1.20 | 0.69 |
Stability (Destabilizing) | 1.0 | -0.95 | 0.94 |
Conservation of Residue | 1.0 | 3.43 | 1.30 |
Conservation of Substitution | -1.0 | -3.97 | -2.35 |
Helix | 1.0 | 2.96 | 2.78 |
Sheet | 1.0 | -0.26 | 4.18 |
C-term | 1.0 | 2.56 | 1.50 |
Active Site | 1.0 | 2.48 | 3.92 |
Active Region | 1.0 | 0.00 | -5.74 |
N-term PLP | 1.0 | 3.00 | 0.94 |
H-interface | 1.0 | 2.55 | -0.43 |
Dimerization Interface | 1.0 | -2.48 | -0.62 |
Δ Polarity | 1.0 | -0.82 | -2.06 |
Δ Charge | 1.0 | 0.57 | 1.61 |
Δ Aromaticity | 1.0 | 4.62 | -0.32 |
Δ Proline | 1.0 | 2.59 | 2.14 |
Δ Codon availability | 1.0 | 0.23 | 0.40 |
Δ Size | 1.0 | -1.26 | 1.34 |