Table 3.
Prevalence of clinically significant behavioral problems by Child Behavior Checklist (CBCL) Syndrome scales in perinatally HIV infected (PHIV) and HIV-exposed uninfected (HEU) young children.
| Syndrome scales n (%) | At enrollment | 12-month visit | pb | ||||
|---|---|---|---|---|---|---|---|
| PHIV n=41 |
HEU n=80 |
pa | PHIV n=41 |
HEU n=80 |
pa | ||
| Emotionally-reactive problem | 1 (2%) | 4 (5%) | 0.66 | 2 (5%) | 9 (11%) | 0.33 | 0.23 |
| Anxious/depressed | 2 (5%) | 3 (4%) | 0.77 | 0 (0%) | 5 (6%) | 0.16 | 0.49 |
| Somatic complaints | 11 (27%) | 11 (14%) | 0.08 | 9 (22%) | 12 (15%) | 0.36 | 0.08 |
| Withdrawn | 4 (10%) | 11 (14%) | 0.77 | 6 (15%) | 12 (15%) | 0.94 | 0.63 |
| Sleep problems | 1 (2%) | 5 (6%) | 0.66 | 0 (0%) | 9 (11%) | 0.03 | 0.06 |
| Attention problems | 1 (2%) | 14 (18%) | 0.09 | 5 (12%) | 12 (15%) | 0.66 | 0.18 |
| Aggressive behaviors | 1 (2%) | 7 (9%) | 0.26 | 2 (5%) | 6 (8%) | 0.71 | 0.29 |
*
T-score of ≥ 70 on each Syndrome scale problem were defined as clinically significant behavioral problems based on criteria documented in the CBCL manual, pa for comparison of proportion of abnormal CBCL between 2 groups using chi-square test, pb using Generalized estimating equations (GEE) for logistic regression to compare abnormal CBCL overtime.