Figure 2. Levels of intensity for the three proteins included in the logistic regression classification model, according to tissue type (T – tumor; non-T – tumor tissue) and relapse/metastasis status (non-Metastatic or Metastatic). (A) HMGB3; (B) COBA1; (C) DHB12. Degrees of significance for the difference concerning median protein levels between two groups (non-Metastatic or Metastatic) were determined by the Mann-Whitney U-test and are represented above the respective bars (**p-value<0.01; *p-value<0.05; n.s. Non-significant). Statistical significance was reached between the non-Metastatic and Metastatic groups within tissue types in HMGB3 and DHB12. For COBA1, statistical significance was only attained when testing the difference between relapse/metastasis status within the tumor tissue type.