Table 1.
Demographics and baseline characteristics of patients with cancer and COVID-19
| All patients (n=205) | Survivors (n=165) | Non-survivors (n=40) | p value | ||
|---|---|---|---|---|---|
| Age, years | 63 (56–70) | 62 (57–69) | 63 (53–75) | 0·82 | |
| Age range, years | |||||
| ≤40 | 16 (8%) | 9 (5%) | 7 (18%) | 0·083 | |
| 41–60 | 70 (34%) | 60 (36%) | 10 (25%) | .. | |
| 61–80 | 103 (50%) | 83 (50%) | 20 (50%) | .. | |
| >80 | 16 (8%) | 13 (8%) | 3 (8%) | .. | |
| Sex | |||||
| Female | 109 (53%) | 98 (59%) | 11 (28%) | 0·0006 | |
| Male | 96 (47%) | 67 (41%) | 29 (73%) | .. | |
| Symptoms | |||||
| Fever | 159 (78%) | 126 (76%) | 33 (83%) | 0·53 | |
| Chills | 17 (8%) | 15 (9%) | 2 (5%) | 0·60 | |
| Cough | 151 (74%) | 119 (72%) | 32 (80%) | 0·42 | |
| Sputum | 70 (34%) | 51 (31%) | 19 (48%) | 0·072 | |
| Chest congestion | 67 (33%) | 49 (30%) | 18 (45%) | 0·096 | |
| Shortness of breath | 71 (35%) | 48 (29%) | 23 (58%) | 0·0014 | |
| Dyspnoea | 39 (19%) | 17 (10%) | 22 (55%) | <0·0001 | |
| Nausea or vomiting | 14 (7%) | 10 (6%) | 4 (10%) | 0·59 | |
| Diarrhoea | 24 (12%) | 21 (13%) | 3 (8%) | 0·52 | |
| Fatigue | 75 (37%) | 60 (36%) | 15 (38%) | 1·00 | |
| Median time from onset of symptoms to admission, days* | 12 (7–19) | 12 (8–20) | 10 (5–14) | 0·011 | |
| Disease severity | |||||
| Non-severe pneumonia | 153 (75%) | 148 (90%) | 5 (13%) | <0·0001 | |
| Severe pneumonia | 52 (25%) | 17 (10%) | 35 (88%) | .. | |
| Comorbidities | 106 (52%) | 90 (55%) | 16 (40%) | 0·14 | |
| Hypertension | 67 (33%) | 56 (34%) | 11 (28%) | 0·55 | |
| Diabetes | 22 (11%) | 20 (12%) | 2 (5%) | 0·31 | |
| COPD | 5 (2%) | 5 (3%) | 0 | 0·59 | |
| Coronary heart disease | 16 (8%) | 11 (7%) | 5 (13%) | 0·37 | |
| Hepatitis B virus infection | 13 (6%) | 12 (7%) | 1 (3%) | 0·45 | |
| Chronic kidney disease | 4 (2%) | 4 (2%) | 0 | 0·72 | |
| Hospital admission before Feb 13, 2020† | |||||
| Yes | 123 (60%) | 87 (53%) | 36 (90%) | <0·0001 | |
| No | 82 (40%) | 78 (47%) | 4 (10%) | .. | |
| Median temperature, °C | 36·6 (36·4–36·9) | 36·6 (36·4–36·8) | 36·7 (36·4–37·5) | 0·085 | |
| Median heart rate, beats per min | 86·0 (79·5–99·5) | 86·0 (78·0–98·5) | 88·0 (80·0–103·0) | 0·65 | |
| Median respiratory rate, breaths per min‡ | 20 (20–22) | 20 (20–22) | 23 (20–28) | <0·0001 | |
| Median SpO2, %§ | 97 (95–98) | 98 (95–98) | 91 (85–95) | <0·0001 | |
Data are median (IQR) or n (%). COPD=chronic obstructive pulmonary disease. SpO2 =blood oxygen saturation.
*
Data on time from onset of symptoms to admission were missing for eight patients.
†
Hospital admission before Feb 13, 2020, is used to represent the time period of the COVID-19 pandemic.
‡
Data on respiratory rate were missing for one patient.
§
Data on SpO2 were missing for 17 patients.