Table 3.
Treatments and complications of patients with cancer and COVID-19
| All patients (n=205) | Survivors (n=165) | Non-survivors (n=40) | p value | |||
|---|---|---|---|---|---|---|
| Median duration of hospital stay, days | 19 (12–33) | 20 (13–33) | 17 (6–29) | 0·032 | ||
| Treatments | ||||||
| Intravenous antibiotics | 144 (70%) | 107 (65%) | 37 (93%) | 0·0012 | ||
| Antiviral medication | 192 (94%) | 153 (93%) | 39 (98%) | 0·45 | ||
| Interferon | 71 (35%) | 48 (29%) | 23 (58%) | 0·0014 | ||
| Oseltamivir | 44 (21%) | 34 (21%) | 10 (25%) | 0·69 | ||
| Umifenovir | 145 (71%) | 116 (70%) | 29 (73%) | 0·94 | ||
| Ribavirin | 52 (25%) | 39 (24%) | 13 (33%) | 0·34 | ||
| Lopinavir plus ritonavir | 49 (24%) | 33 (20%) | 16 (40%) | 0·014 | ||
| Intravenous immunoglobin | 60 (29%) | 33 (20%) | 27 (68%) | <0·0001 | ||
| Intravenous corticosteroids | 62 (30%) | 38 (23%) | 24 (60%) | <0·0001 | ||
| Oxygen therapy | 150 (73%) | 112 (68%) | 38 (95%) | 0·0011 | ||
| Mechanical ventilation | ||||||
| None | 173 (84%) | 162 (98%) | 11 (28%) | <0·0001 | ||
| Non-invasive | 11 (5%) | 3 (2%) | 8 (20%) | .. | ||
| Invasive | 21 (10%) | 0 | 21 (53%) | .. | ||
| Admission to ICU | 30 (15%) | 4 (2%) | 26 (65%) | <0·0001 | ||
| CCRT | 5 (2%) | 1 (1%) | 4 (10%) | 0·0039 | ||
| Complications | 126/199 (63%) | 92/161 (57%) | 34/38 (89%) | 0·0004 | ||
| ARDS | 23/199 (12%) | 2/161 (1%) | 21/38 (55%) | <0·0001 | ||
| Acute renal failure | 13/199 (7%) | 1/161 (1%) | 12/38 (32%) | <0·0001 | ||
| Septic shock | 11/199 (6%) | 0 | 11/38 (29%) | <0·0001 | ||
| Abnormal liver function | 34/199 (17%) | 19/161 (12%) | 15/38 (39%) | 0·0001 | ||
| Coagulopathy | 18/199 (9%) | 5/161 (3%) | 13/38 (34%) | <0·0001 | ||
| Secondary infection | 26/199 (13%) | 5/161 (3%) | 21/38 (55%) | <0·0001 | ||
| Arrhythmia | 5/199 (3%) | 1/161 (1%) | 4/38 (11%) | 0·0034 | ||
| Other complications* | 34/199 (17%) | 13/161 (8%) | 21/38 (55%) | <0·0001 | ||
Data are median (IQR) or n/N (%), where N is the number of patients with available data. ICU=Intensive-care unit. CCRT=continuous renal replacement therapy. ARDS=acute respiratory distress syndrome.
*
Stroke, acute heart failure, myocardial ischaemia, electrolyte disturbance, and other complications.