Fig. 2. MRN and Ctp1 promote resistance to dFdC and removal from genomic DNA.
(A) mrn/ctp1 deletion mutants are sensitive to dFdC. Representative example of three experiments. (B) The dFdC/hdC ratio is significantly increased in mrn/ctp1 deletion mutants compared to WT. Error bars depict SE; asterisk indicates statistically significant difference with WT (t test, P < 0.05; n = 3).