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. 2020 May 4;130(6):3021–3037. doi: 10.1172/JCI125505

Figure 10. RSV infection–induced Gas6/Axl axis suppresses IFN-γ production in NK cells after S. pneumoniae infection.

Figure 10

(A) Representative flow cytometry analysis of IFN-γ production by NK cells, CD4+ T cells, and CD8+ T cells during secondary bacterial infection after RSV infection in the control IgG-treated or anti-Axl mAb-treated mice. (B) Numbers of cells positive for IFN-γ in the lungs of control mice and (C) Axl mAb-treated mice on day 1 after S. pneumoniae infection. The data are expressed as mean ± SEM; n = 4–5. Representative results from 2 independent experiments are shown. The following statistical tests were used: One-way ANOVA (B), 2-tailed Student’s t test (C). **P < 0.01; ***P < 0.001.