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Ins(1,4,5)P3 (1) and analogues methyl α-l-glucopyranoside 2,3,6-trisphosphate (2) and methyl α-l-glucopyranoside 2,4,6-trisphosphate (3) with their structural differences contribute to their Ins(1,4,5)P3R partial agonist activity in dark red.
