Fig. 11.

Examples of tractography results for a subset of the subjects found to have anatomical abnormalities, demonstrating that cohort-averaged tracts do not respect underlying anatomical abnormalities. In each case the anatomical abnormality (as described on the HCP quality control website) is given and indicated by the white arrows, and affected tracts are presented. Both the individual subject’s extracted tract (indicated by “S”) and the corresponding cohort-averaged tract (indicated by “A”) are overlaid on a zoomed in individual T1-weighted scan (the orange boxes show the zoomed regions). Tracts are displayed with a threshold of 0.1%. a.) a cyst in the right parietal lobe affecting the MdLF. b.) small cavernoma in the brain stem affecting the MCP. c.) a small cavernoma in the right parietal lobe affecting the CST. d.) a developmental venous anomaly (DVA) in the right frontal lobe affecting the ATR. e.) a cavernoma in the left occipital lobe affecting the OR.