Pin1 positively correlates with IL‐18 expression in pancreatic cancer patients. (A) Representative images of IHC staining for Pin1 and IL‐18 in pancreatic cancer tissues (scale bar, 200 µm; inset scale bar, 40 µm). (B) Correlation analysis of Pin1 expression and IL‐18 expression in PDAC tissues, as determined by the IHC score (n = 39, P < .0001). (C) Representative images of IHC staining for IL‐18 in PDAC and adjacent normal tissues (scale bar, 200 μm; inset scale bar, 40 µm). (D) IL‐18 expression in PDAC and adjacent normal tissues, as determined by the IHC score (n = 39, P < .0001). (E‐F) The prognostic value of IL‐18 showed that high expression of IL‐18 predicted a worse prognosis for pancreatic cancer by analysis of the TCGA data set