Table 1.
Patient demographics and outcome measure scores at baseline visit
| All patients(n=112) | GCA (n=56) | TAK (n=56) | p-value | |
|---|---|---|---|---|
| Patient Demographics | ||||
| Age | 55 (34–71) | 71 (63.3–76) | 34 (22.3–43.8) | <0.01 |
| Sex (% female) | 79.5% (n=89) | 78.5% (n=44) | 80.4% (n=45) | 1.00 |
| Race (% Caucasian) | 73.2% (n=82) | 78.6% (n=44) | 67.9% (n=38) | 0.29 |
| BMI | 25.8 (22.4–29.4) | 26.3 (24.8–29.2) | 25.7 (21.6–29.5) | 0.31 |
| Prednisone Dose (mg/day) | 5 (0–19.4) | 5 (0–28.8) | 2.5 (0–10) | 0.05 |
| Other immunosuppressant | 54.5% (n=61) | 44.6% (n=25) | 64.3% (n=36) | 0.06 |
| Disease duration (years) | 2.4 (0.7–8.3) | 1.4 (0.5–2.9) | 5.3 (1.6–15.2) | <0.01 |
| Patient Reported Outcomes | ||||
| Patient Global Assessment | 4 (1–6) | 4 (1–5.8) | 4 (1.8–6.3) | 0.58 |
| MFI | 14 (12–17) | 14 (9–16) | 15 (12–17.8) | 0.10 |
| BIPQ | 41 (31–50) | 41 (30–50) | 43 (34.8–50) | 0.24 |
| SF-36 PCS | 50.2 (43.5–57.3) | 50 (42.7–54.3) | 50.7 (44.1–57.9) | 0.37 |
| SF-36 MCS | 50 (40.1–56.7) | 51.1 (41.5–58.9) | 48 (37.5–55.2) | 0.15 |
| Physician Reported Outcomes | ||||
| Physician Global Assessment | 0 (0–3) | 0 (0–3) | 0 (0–3) | 0.60 |
| Active Disease at Visit (Physician Global >0) |
42% (n=47) | 46.4% (n=26) | 37.5% (n=21) | 0.44 |
| Laboratory Outcomes | ||||
| CRP (mg/L) | 4.1 (1.1–11) | 5.0 (1–10.4) | 3.75 (1.2–13.8) | 0.83 |
| ESR (mm/hour) | 18 (7.3–29) | 15.5 (7.3–31.8) | 18 (7.5–29) | 0.90 |
| Imaging Outcomes | ||||
| PETVAS | 17 (13–24) | 19 (14–26.5) | 15 (9–19) | <0.01 |
Values are reported as median and interquartile range or as percentage and n-value. Mann-Whitney test was used to compare continuous variables. Two-tailed fisher exact test was used to compare categorical variables. Values may not be based on total denominations if there were missing responses.
GCA= giant cell arteritis; TAK= Takayasu’s arteritis; BMI= body mass index; MFI= Multi-dimensional fatigue inventory; BIPQ= brief illness perception questionnaire; SF-36 PCS= 36-item short form health survey physical component summary score; SF-36 MCS= 36-item short form health survey mental component summary score; CRP= c-reactive protein; ESR= erythrocyte sedimentation rate; PETVAS= qualitative score of vascular FDG-PET activity; mg= milligram; L=liters; mm=millimeter.