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. Author manuscript; available in PMC: 2021 May 1.
Published in final edited form as: J Clin Immunol. 2020 Apr 2;40(4):592–601. doi: 10.1007/s10875-020-00773-y

Table 1.

Diagnoses criteria for each PAD.

PAD Diagnoses Criteria
CVID IgG less than 2SD, IgA or IgM less than 2SD and <70% of Pneumovax serotype response
IgGD IgG less than 2SD with IgA and IgM within normal limits
IgG2D Total IgG within normal range and IgG subclass less than 2SD
SAbD Total IgG, IgM and IgA within normal range and <70% of Pneumovax serotype response

In our institution, two standard deviations (2SD) for IgG, IgA, IgM and IgG subclass 2 for age equal and greater than 18 years old were defined as 768–1623, 70–408, 40–263 and 241–700 mg/dL, respectively.