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. Author manuscript; available in PMC: 2021 May 28.
Published in final edited form as: J Phys Chem B. 2020 May 18;124(21):4270–4283. doi: 10.1021/acs.jpcb.0c02632

Figure 2.

Figure 2

Snapshots of the addition process of TTP addition to a DNA strand by HIV RT : (a) The reactant state structure, (b) the transition state, (c) the product state. (d) The transition state structure of the sulfur variant of TTP - α-thio(Sp) TTP.