Table 2. Down-regulated miRNAs reported in all studies in all specimen types with fold changes.
| MiRNA | Number of studies | Sample size EC | Sample size control | Mean fold change** | Studies with fold change reported |
|---|---|---|---|---|---|
| miR-137 | 1 | 23 | 4 | 115.15 | 1 |
| miR-129-3p | 1 | 23 | 4 | 42.30 | 1 |
| miR-410 | 1 | 73 | 31 | 13.91 | 1 |
| miR-503 | 1 | 14 | 10 | 8.60 | 1 |
| miR-1247 | 1 | 30 | 20 | 5.31 | 1 |
| miR-376c | 1 | 30 | 20 | 3.64 | 1 |
| miR-377 | 1 | 30 | 20 | 3.34 | 1 |
| miR-26a-5p | 1 | 49 | 6 | 3.10 | 1 |
| miR-214 | 1 | 30 | 20 | 2.90 | 1 |
| miR-150-5p | 1 | 49 | 6 | 2.70 | 1 |
| miR-370 | 1 | 30 | 20 | 2.68 | 1 |
| let-7f-5p | 1 | 49 | 6 | 2.60 | 1 |
| miR-26b-5p | 1 | 49 | 6 | 2.60 | 1 |
| let-7c-5p | 1 | 49 | 6 | 2.50 | 1 |
| miR-23b-3p | 1 | 49 | 6 | 2.40 | 1 |
| miR-125b-5p | 1 | 49 | 6 | 2.30 | 1 |
| miR-126-3p | 1 | 49 | 6 | 2.30 | 1 |
| miR-195-5p | 1 | 49 | 6 | 2.20 | 1 |
| miR-424-5p | 1 | 49 | 6 | 2.20 | 1 |
| miR-374a-5p | 1 | 49 | 6 | 2.10 | 1 |
| let-7a-5p | 1 | 49 | 6 | 2.00 | 1 |
| let-7e-5p | 1 | 49 | 6 | 2.00 | 1 |
| miR-125a-5p | 1 | 49 | 6 | 2.00 | 1 |
| miR-542-5p | 1 | 14 | 10 | 2.00 | 1 |
| miR-337-5p | 1 | 30 | 20 | 1.94 | 1 |
| miR-1305 | 1 | 73 | 31 | 1.77 | 1 |
| miR-758 | 1 | 30 | 20 | 1.61 | 1 |
| miR-300 | 1 | 30 | 20 | 1.56 | 1 |
| miR-93 | 1 | 176 | 100 | NR | 0 |
| miR-125 | 1 | 67 | 15 | NR | 0 |
| miR-34 | 1 | 67 | 15 | NR | 0 |
| miR-30a-3p | 1 | 40 | 26 | NR | 0 |
| miR-301b | 1 | 34 | 14 | NR | 0 |
| miR-10b | 1 | 28 | 14 | NR | 0 |
| miR-195 | 1 | 28 | 14 | NR | 0 |
| miR-30a-5p | 1 | 28 | 14 | NR | 0 |
| miR-101 | 1 | 21 | 7 | NR | 0 |
| miR-10b* | 1 | 21 | 7 | NR | 0 |
| miR-133a | 1 | 21 | 7 | NR | 0 |
| miR-133b | 1 | 21 | 7 | NR | 0 |
| miR-152 | 1 | 21 | 7 | NR | 1 |
| miR-29b | 1 | 21 | 7 | NR | 0 |
| miR-34b | 1 | 21 | 7 | NR | 0 |
| miR-411 | 1 | 21 | 7 | NR | 0 |
NR = not reported, ** mean fold change as found by qRT-PCR.