Table 4. EGFR mutation subtypes .
Exon Mutation Subtype | N (%) | Stage at Presentation |
---|---|---|
Exon 19 deletion | 63 (44) | Stage 1 = 48 (76%) |
Stage 2 = 7 (11%) | ||
Stage 3 = 8 (13%) | ||
Exon 20 insertion | 7 (5) | Stage 1 = 4 (57%) |
Stage 2 = 0 (0%) | ||
Stage 3 = 3 (43%) | ||
G719A | 2 (1) | Stage 1 = 2 (100%) |
Stage 2 = 0 (0%) | ||
Stage 3 = 0 (0%) | ||
L858R | 49 (35) | Stage 1 = 34 (70%) |
Stage 2 = 5 (10%) | ||
Stage 3 = 10 (20%) | ||
G719× | 6 (4) | Stage 1 = 6 (100%) |
Stage 2 = 0 (0%) | ||
Stage 3 = 0 (0%) | ||
L861Q | 8 (6) | Stage 1 = 7 (88%) |
Stage 2 = 0 (0%) | ||
Stage 3 = 1 (12%) | ||
T790M | 2 (1) | Stage 1 = 2 (100%) |
Stage 2 = 0 (0%) | ||
Stage 3 = 0 (0%) | ||
Multiple mutations | 5 (4) | Stage 1 = 4 (80%) |
Stage 2 = 1 (20%) | ||
Stage 3 = 0 (0%) |