Table 2. Expression of stemness genes in biopsies of breast tumors.
Genes | No metastasis (n = 66) | Yes metastasis (n = 32) | p-value | No metastasis (n = 66) | Yes metastasis (n = 32) | p-value | ||
---|---|---|---|---|---|---|---|---|
OCT3 | Before NAC | 5.98 ± 2.89 | 12.31 ± 8.15 | 0.366 | After NAC | 10.63 ± 5.01 | 64.12 ± 35.68 | 0.040 |
SMO | 0.57 ± 0.09 | 0.80 ± 0.14 | 0.167 | 0.80 ± 0.15 | 1.53 ± 0.43 | 0.047 | ||
MYC | 0.41 ± 0.04 | 0.72 ± 0.16 | 0.012 | 0.63 ± 0.10 | 1.94 ± 0.78 | 0.020 | ||
SNAI2 | 0.49 ± 0.08 | 0.73 ± 0.16 | 0.144 | 0.99 ± 0.15 | 1.77 ± 0.43 | 0.035 | ||
KLF4 | 0.76 ± 0.12 | 1.07 ± 0.28 | 0.224 | 2.21 ± 0.44 | 3.82 ± 2.47 | 0.378 | ||
BMI1 | 2.14 ± 0.37 | 4.07 ± 0.75 | 0.011 | 34.63 ± 31.93 | 8.06 ± 3.55 | 0.565 | ||
VIM | 0.30 ± 0.04 | 0.41 ± 0.06 | 0.137 | 0.69 ± 0.11 | 1.56 ± 0.59 | 0.049 | ||
FLT3 | 2.49 ± 0.50 | 2.18 ± 0.85 | 0.746 | 2.59 ± 0.76 | 4.52 ± 1.60 | 0.218 | ||
SMAD2 | 0.19 ± 0.03 | 0.37 ± 0.27 | 0.338 | 0.35 ± 0.06 | 0.32 ± 0.12 | 0.778 | ||
KLF1 | 0.29 ± 0.08 | 0.31 ± 0.10 | 0.864 | 0.44 ± 0.22 | 0.53 ± 0.33 | 0.811 | ||
TERT | 0.43 ± 0.10 | 1.26 ± 0.61 | 0.061 | 0.35 ± 0.07 | 1.53 ± 0.68 | 0.016 | ||
TGFB1 | 1.00 ± 0.14 | 1.63 ± 0.38 | 0.062 | 1.61 ± 0.26 | 3.08 ± 0.95 | 0.047 | ||
TGFBR1 | 0.85 ± 0.13 | 1.02 ± 0.19 | 0.458 | 1.22 ± 0.17 | 1.99 ± 0.79 | 0.201 |