Figure 5. The role of TAK1 in cancer cell and macrophage vasculature.

(A) Vasculature is increased in the MDA-MB-231 TAK1^KO, in comparison to TAK1^WT. (B) Vasculature was quantified by counting blood vessels; researcher was blinded. (C) Angiogenesis factors profile for MDA-MB-231 TAK1^WT vs TAK1^KO and for (D) LPS stimulated THP-1 vehicle vs takinib. RFU = Relative fluorescent unit. n = 5 ± SEM, ^* p = 0.05.