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. Author manuscript; available in PMC: 2021 May 1.
Published in final edited form as: Harv Rev Psychiatry. 2020 May-Jun;28(3):203–214. doi: 10.1097/HRP.0000000000000255

Table 2.

Summary of Mobile-Based Interventions for Anxiety or Depression in Older Adults

Study Sample size Population Intervention(s) Results
Spek et al. (2007)69 n = 301 Older adults with subthreshold depression iCBT vs. group CBT vs. waitlist control Participants in treatment conditions saw significantly greater improvements in depressive symptoms than those in the control condition
No significant difference between the two treatment conditions
Zou et al. (2012)70 n = 22 Older adults with symptoms of GAD iCBT for anxiety Participants saw significant improvements in anxiety, stress, and depression symptoms
Dear et al. (2013)71 n = 20 Older adults with symptoms of depression iCBT for depression Participants saw significant improvements in depressive symptoms
Mewton et al. (2013)72 n = 225 Older adults prescribed iCBT by their primary care clinicians iCBT for major depression, generalized anxiety, panic disorder, or social phobia Participants saw significant reductions in psychological distress and disability
Brenes et al. (2015)73 n = 141 Rural older adults with GAD Telephone-delivered CBT vs. telephone-delivered NDST Participants who received telephone-delivered CBT saw greater improvements in anxiety and depressive symptoms than those receiving telephone-delivered NST
Titov et al. (2015)74 n = 54 Older adults with symptoms of depression iCBT for depression vs. waitlist control Compared to control group, treatment group had significantly lower levels of depression and anxiety symptoms at posttreatment and follow-ups
Titov et al. (2016)75 n = 433 Older adults with symptoms of anxiety and depression Clinician-guided CBT vs. initial clinician interview plus self-guided iCBT vs. iCBT alone Participants in all groups saw significant improvements in depression and anxiety symptoms
No significant differences between groups
Jones et al. (2016)76 n = 46 Older adults with GAD iCBT for anxiety vs. waitlist control Compared to control group, treatment group had significantly lower levels of anxiety and depression at posttreatment and one-month follow-up
Wahbeh (2018)77 n = 50 Older adults with mild to moderate symptoms of depression Internet-based mindfulness meditation vs. waitlist control Participants who received internet-based mindfulness meditation saw greater improvements in depressive symptoms, perceived stress, insomnia symptoms, and pain severity than those in waitlist control condition

CBT, cognitive-behavioral therapy; GAD, generalized anxiety disorder; iCBT, internet-delivered CBT; NST, nondirective supportive therapy