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DHED treatment decreased phosphorylated tau protein expression in the hippocampus of AD mice. a Western blot showed the relative expression of total tau, p-ser235 tau, and p-ser396 tau in the hippocampus of the mice. b The protein expressions were normalized to GAPDH and the fold changes were calculated relative to the control. Data are displayed as mean values ± SEM. ANOVA, *p < 0.05 vs control or vehicle or DHED+ICI182780
