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. 2020 May 29;11:2666. doi: 10.1038/s41467-020-16434-y

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Significantly overexpressed fusion genes. Violin plots defined as: FGFR3 no fusion (n = 730, minimum = 0.00, maximum = 3.26, median = 0.05), fusion (12, 1.26, 3.34, 2.58); MAPKAPK2 no fusion (737, 1.16, 2.85, 1.83), fusion (5, 1.75, 2.66, 2.36); MYC no fusion (723, 0.03, 3.00, 1.39), fusion (19, 1.30, 2.69, 1.89); NTRK1 no fusion (739, 0.00, 1.55, 0.03), fusion (3, 0.68, 2.13, 1.39); PAX5 no fusion (739, 0.00, 1.88, 0.11), fusion (3, 0.42, 1.71, 1.05); PIM3 no fusion (739, 0.00, 2.32, 0.99), fusion (3, 1.51, 1.99, 1.73); RARA no fusion (739, 0.00, 1.83, 0.75), fusion (3, 0.67, 1.63, 1.31); TXNIP no fusion (735, 1.31, 3.43, 2.41), fusion (7, 2.3, 3.87, 3); WHSC1 no fusion (645, 0.33, 2.57, 0.91), fusion (97, 1.21, 2.77, 2.19). All data points from 0 to 100th percentile are shown. b Expression percentile distribution for different gene classes. Violin plots defined as: Kinase (n = 298, minimum = 0.01, maximum = 1.00, median = 0.74); Oncogene (224, 0.03, 1.00, 0.92); Tumor Suppressor (137, 0.01, 1.00, 0.61). All data points from 0 to 100th percentile are shown. c. 5′ and 3′ gene expression of fusions with intact 3′ kinase genes. The two empty circles have no expression value for the 5′ gene (IGH, IGL). Labels refer to genes appearing more than once. Source data and scripts are available at 10.6084/m9.figshare.11941494.