Table 1.

Hormonal measurement in WT and KO mice in plasma levels by LC-MS/MS.

Hormones (in nmol/l)	XX mice		P-value	XY mice		P-value
	Cyp17A (+/+) (n = 9) (mean ± SEM)	Cyp17A (d/d) (n = 6) (mean ± SEM)		Cyp17A (+/+) (n = 6) (mean ± SEM)	Cyp17A (d/d) (n = 12) (mean ± SEM)
Progesterone	8.53 ± 5.59	37.61 ± 0.9.88	0.001	1.08 ± 0.21	2.36 ± 1.53	0.067
Desoxycorticosterone	8.47 ± 3.50	12.69 ± 2.89	0.216	2.03 ± 0.64	11.60 ± 7.49	0.008
Corticosterone	405.55 ± 81.94	617.35 ± 137.48	0.128	254.47 ± 42.62	699.43 ± 313.30	0.002
Aldosterone	0.42 ± 0.13	0.57 ± 0.15	0.382	0.41 ± 0.12	1.01 ± 0.94	0.154
Testosterone	0.12 ± 0.05	0.10 ± 0.03	0.770	11.53 ± 6.22	0.04 ± 0.03	0.015
Estrone	0.11 ± 0.02	0.0 ± 0.0	0.001	—	—	—