Table 3.

Lipid parameter levels measurement in WT and KO on Apoe (d/d) genetic background after feeding a WTD.

Lipid parameter	Status	XX mice		P-value	XY mice		P-value
		Cyp17a1 (+/+) x Apoe (d/d) (n = 7) (mean ± SEM)	Cyp17a1 (d/d) x Apoe (d/d) (n = 7) (mean ± SEM)		Cyp17a1 (d/d) x Apoe (d/d) (n = 7) (mean ± SEM)	Cyp17a1 (+/+) x Apoe (d/d) (n = 6) (mean ± SEM)
TC	Pre-Diet	6.59 ± 0.30	7.56 ± 0.19	<0.001	7.68 ± 0.48	7.72 ± 0.51	0.961
	Post-Chow	7.08 ± 0.76	7.02 ± 0.40	0.944	9.48 ± 1.24	8.84 ± 1.08	0.718
	Post-WTD	20.83 ± 0.92	22.24 ± 1.27	0.433	22.14 ± 1.45	19.61 ± 2.40	0.372
LDLC	Pre-Diet	3.3 ± 0.28	4.03 ± 0.25	0.062	3.96 ± 0.38	3.78 ± 0.36	0.734
	Post-Chow	3.7 ± 0.29	4.27 ± 0.29	0.202	4.64 ± 0.55	5.88 ± 0.18	0.063
	Post-WTD	9.73 ± 0.83	10.41 ± 0.70	0.540	11.00 ± 0.55	10.77 ± 1.06	0.845
HDLC	Pre-Diet	0.69 ± 0.04	0.63 ± 0.04	0.225	0.68 ± 0.03	0.68 ± 0.04	0.963
	Post-Chow	0.77 ± 0.44	0.44 ± 0.04	0.432	3.25 ± 1.23	0.55 ± 0.09	0.062
	Post-WTD	0.28 ± 0.04	0.37 ± 0.05	0.149	0.47 ± 0.09	0.45 ± 0.06	0.867
TG	Pre-Diet	1.3 ± 0.24	1.43 ± 0.11	0.576	1.41 ± 0.12	1.38 ± 0.14	0.855
	Post-Chow	1.46 ± 0.24	1.16 ± 0.05	0.222	2.77 ± 0.51	1.90 ± 0.18	0.143
	Post-WTD	2.1 ± 0.16	2.11 ± 0.24	0.950	2.55 ± 0.89	2.18 ± 0.42	0.262