Anti-inflammatory effects of SVF on synoviocytes secreted PGE2, CXCL8/IL-8 and IL-6. aSVF significantly down-regulates the expression of the main osteoarthritis inflammatory cytokines and chemokines. PGE2, CXCL8/IL-8 and IL-6 release is decreased by tSVF, aSVF, and ASCs co-culture. *p < 0.05, **p < 0.01 compared with each monoculture of synoviocytes