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. 2020 Mar 5;4(3):499–507. doi: 10.1002/bjs5.50269

Table 1.

Basal and postoperative values of C‐reactive protein, procalcitonin and Dutch leakage score according to the endpoints

Anastomotic leakage Morbidity Mortality
Yes No P Yes No P Yes No P
CRP
Basal 10·32(28·43) 10·76(22·42) 0·544 14·35(28·79) 9·16(19·67) 0·003 25·35(40·35) 10·54(22·57) 0·009
POD2 176·51(126·69) 109·01(68·01) < 0·001 143·57(89·08) 96·49(61·79) < 0·001 201·22(83·91) 111·27(72·61) < 0·001
POD3 212·29(111·94) 98·61(71·51) < 0·001 143·83(94·95) 86·45(61·12) < 0·001 209·33(109·22) 102·80(76·51) < 0·001
POD6* 156·06(89·11) 61·36(57·81) < 0·001 97·79(78·71) 45·67(41·17) < 0·001 192·66(74·43) 67·94(65·05) 0·001
PCT
Basal 0·11(0·21) 0·13(0·40) 0·648 0·14(0·35) 0·12(0·41) 0·089 0·31(1·00) 0·13(0·38) 0·265
POD2 5·65(12·04) 1·36(3·26) < 0·001 2·81(6·59) 1·03(2·37) < 0·001 12·49(19·06) 1·45(3·58) < 0·001
POD3 5·56(11·05) 0·94(2·54) < 0·001 2·24(5·86) 0·67(1·56) < 0·001 11·39(19·56) 1·03(2·76) < 0·001
POD6* 4·12(6·19) 0·86(5·89) 0·002 1·87(8·15) 0·52(3·31) < 0·001 12·70(12·93) 1·02(5·83) 0·002
DLS
Basal 0·39(0·89) 0·25(0·72) 0·123 0·36(0·89) 0·21(0·65) 0·001 1·20(1·91) 0·24(0·69) < 0·001
POD2 3·48(2·79) 1·53(1·39) < 0·001 2·35(2·06) 1·31(1·12) < 0·001 4·55(3·48) 1·59(1·48) < 0·001
POD3 4·07(3·08) 1·15(1·31) < 0·001 2·25(2·22) 0·87(0·90) < 0·001 5·62(3·93) 1·24(1·46) < 0·001
POD6* 3·40(3·51) 0·87(1·22) < 0·001 1·79(2·22) 0·50(0·61) < 0·001 7·64(4·40) 1·01(1·47) < 0·001

Values are mean(s.d.).

*

Data available for 566 patients. CRP, C‐reactive protein; PCT, procalcitonin; DLS, Dutch leakage score.

Mann–Whitney U test.