Levels of endothelial dysfunction and neutrophil degranulation biomarkers in healthy control, infection, sepsis and septic shock groups
Biomarkers of a endothelial dysfunction and b neutrophil degranulation. Levels of mid‐regional proadrenomedullin (MR‐ProADM) are in nmol/l, those of interleukin‐18 receptor type 1 (IL18R1) are copies of cDNA per ng mRNA, and those of the remaining biomarkers are in pg/ml. ANGPT, angiopoietin; ESM, endothelial cell‐specific molecule; ICAM, intercellular adhesion molecule; SEL‐E, E‐selectin; SDC, syndecan; VCAM, vascular cell adhesion molecule; SEL‐P, P‐selectin; THBD, thrombomodulin; MMP, matrix metalloproteinase; LTF, lactoferrin; PRTN, proteinase; LCN, lipocalin; MPO, myeloperoxidase. *P ≤ 0·050 versus healthy control; †P ≤ 0·050 (Kruskal–Wallis test).