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. 2020 Feb 19;4(3):524–534. doi: 10.1002/bjs5.50265

Figure 3.

BJS5-50265-FIG-0003-c

Area‐under‐the‐curve analysis evaluating the accuracy of two biomarkers in differentiating sepsis from infection or from septic shock a Accuracy of mid‐regional proadrenomedullin (MR‐ProADM) in differentiating sepsis from infection. Area under the curve (AUC): 0·86, 95 per cent c.i. 0·80 to 0·91 (P < 0·001); optimal operating point (OOP): 1·165 nmol/l; sensitivity: 84·6 per cent; specificity: 76·0 per cent. b Accuracy of lipocalin 2 in differentiating septic shock from sepsis. AUC: 0·81, 95 per cent c.i. 0·73 to 0·90 (P < 0·001); OOP: 246 346 pg/ml; sensitivity: 80·0 per cent; specificity: 70·5 per cent.