Table 1.
Clinical characteristics of the original sample (N = 274) and the subsample (N = 147) with available data concerning GABA concentration and BDNF serum concentration used in this study.
| GABA sample | GABA-BDNF subsample | |
|---|---|---|
| N | 274 | 147 |
| Age Mean (SD) [years] | 24.68 (4.57) | 24.45 (4.35) |
| Females | 179 (65.3%) | 99 (67.3%) |
| MDD current or remitted (N) | 75 (27.4%) | 29 (19.7%) |
| Medicated Subjects | 3 (1.1%) | 2 (1.4%) |
| Mean BDNF serum concentration (pg/ml) | - | 11500 (3400) |
| BDNF rs6265 genotypes (subsample N = 109/79) | c/c 61 c/t 43 t/t 5 | c/c 43 c/t 33 t/t 3 |
| BDI Mean (SD) | 4.81 (6.87), 2 missing | 3.81 (6.53), 2 missing |
| MADRS Mean (SD) | 3.44 (5.56), 1 missing | 2.96 (5.90), 1 missing |
| Volume left prefrontal cortex (gyri and sulci, cm3) | 52.84 (6.10), 1 missing | 53.18 (6.17) |
| Surface left prefrontal cortex (gyri and sulci, cm2) | 165.16 (17.95), 1 missing | 165.71 (17.33) |