Table 1.
Patients’ characteristics at admission, during ICU stay and at follow-up
Case 1 | Case 2 | Case 3 | Case 4 | Case 5 | Case6 | |
---|---|---|---|---|---|---|
Age, years | 35 | 48 | 56 | 62 | 43 | 62 |
Sex | Male | Male | Male | Male | Male | Male |
Premorbid condition |
Cocaine Tobacco |
Type II diabetes mellitus |
Tobacco Coronary heart disease |
Tobacco Ischemic dilated cardiomyopathy |
None | Ischemic dilated cardiomyopathy |
Reason for VA-ECMO | Refractory cardiac arrest (cocaine-induced vasospasm) | Septic cardiomyopathy | Ischemic cardiogenic shock | Primary heart graft dysfunction | Ischemic cardiogenic shock | Cardiogenic shock |
Pre-ECMO SAPS II score | 64 | 86 | 84 | 52 | 85 | 34 |
Pre-ECMO SOFA score | 14 | 17 | 16 | 16 | 9 | 10 |
Duration of VA-ECMO support, days | 4 | 29 | 2 | 47 | 4 | 13 |
Survival to hospital discharge | Yes | Yes | Yes | No | Yes | Yes |
ICU length of stay (days) | 90 | 74 | 6 | 51 | 9 | 30 |
Organ support during ICU stay | ||||||
Renal replacement therapy | Yes | Yes | No | Yes | Yes | No |
Mechanical ventilation duration (days) | 78 | 51 | 3 | 51 | 8 | 1 |
ECMO cannulation site | Femoral | Femoral | Femoral | Femoral | Femoral | Femoral |
ECMO flow rate at initiation (L/min) | 4.23 | 3.9 | 4 | 3.8 | 3.1 | 4.1 |
IABP | No | No | No | No | Yes | Yes |
Coronary angiography before SCI | Yes | Yes | Yes | No | Yes | No |
Localization (artery) | Radial | Femoral | Femoral | NK | ||
Critical illness polyneuropathy at sedation withdrawal that could have delayed SCI diagnosis | Yes | Yes | No | Yes | No | No |
Delay between awakening and SCI diagnosis (days) | 36 | 48 | 0 | 33 | 0 | NA* |
Biology at ECMO start | ||||||
pH | 7.23 | 7.26 | 7.50 | 7.20 | 6.87 | 7.63 |
PaCO2, mmHg | 23.5 | 31.8 | 31.3 | 33 | 70 | 31.8 |
PaO2, mmHg | 375 | 73 | 68.8 | 142 | 40 | 61.7 |
Lactate, mmol/L | 4.4 | 9 | 0.9 | 12.5 | 15 | 1 |
Platelets count, 109/mL | 234 | 45 | 73 | 260 | 100 | 51 |
APTT (patient/reference) ratio | 1.9 | 1.2 | 1.7 | 1,7 | ND | 2.48 |
Prothrombin time, % | 66 | 30 | 65 | 46 | 50 | 76 |
Fibrinogen, g/L | 2.4 | 5.8 | 5.5 | 1.8 | 1.8 | 5.6 |
Biology at SCI diagnosis | ||||||
pH | 7.51 | 7.46 | 7.49 | 7.49 | 7.4 | ND |
PaCO2, mmHg | 76.8 | 43.6 | 35.8 | 27.1 | 37 | ND |
PaO2, mmHg | 41.3 | 40 | 129 | 70 | 90 | ND |
Lactate, mmol/L | 1.9 | 1.2 | 0.9 | 1.6 | 1.5 | ND |
Platelets, 109/mL | 442 | 347 | 168 | 69 | 259 | 212 |
APTT (patient/reference) ratio | 2 | 1.3 | 1 | 1.17 | 1.7 | 1.6 |
Prothrombin time, % | 57 | 78 | 87 | 76 | 80 | 60 |
Fibrinogen, g/L | 7.4 | 7 | 7.8 | 3.6 | 4 | 4.3 |
- year follow-up | Wheelchair urinary tract self-catheterization | Wheelchair urinary tract self-catheterization | Wheelchair urinary tract self-catheterization | NA | Wheelchair | Pain in the lower limbs |
Patient was always awake without sedation
ICU intensive care unit, VA-ECMO venoarterial-extracorporeal membrane oxygenation, SAPS simplified acute physiology score, SOFA sequential organ-failure assessment, SCI spinal cord infarction, IABP intra-aortic balloon counterpulsation, APTT activated partial thrombin time, NA not applicable, NK not known