Table 1.
Clinical features | Patient 1 | Patient 2 | Patient 3 | Patient 4 | Patient 5 |
---|---|---|---|---|---|
Sex | Female | Female | Female | Male | Female |
Age, y | 45 | 41 | 60 | 55 | 58 |
Liver disease | AIH | AIH | AIH | AIH | PBC |
Liver stiffness, kPa | 5.8 | 4.4 | 5.2 | 40.0 | 4.3 |
CAP, dB/m | 161 | 165 | 274 | 185 | 159 |
Cirrhosis | No | No | No | Yes | No |
Arterial hypertension | No | No | No | No | No |
Diabetes mellitus | No | Yes | No | No | No |
Obesity | No | No | Yes | No | No |
Rheumatologic disease | No | No | No | No | Yes |
Prednisone, mg/d | 8.75 | 6.25 | 2.5 | 50 | 5a |
Azathioprine, mg/d | 0 | 125 | 75 | 0 | 100a |
Before SARS-CoV-2b | |||||
Hospital outpatient visit | No | No | Yes | Yes | No |
Hospitalization | No | No | No | No | No |
Workingc | Yes | Yes | No | Yes | No |
SARS-CoV-2 management | |||||
Hospitalization | Yes | No | No | Yes | No |
Hydroxychloroquine | Yes | Yes | Yes | Yes | Yes |
Lopinavir/ritonavir | Yes | No | No | Yes | No |
Azithromycin | No | Yes | Yes | No | No |
Outcome | Alive | Alive | Alive | Alive | Alive |
NOTE. Each patient was assigned a number.
AIH, autoimmune hepatitis; CAP, controlled attenuation parameter; PBC, primary biliary cholangitis; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.
Immunosuppressive therapy for undifferentiated connective tissue disease.
In late February 2020.
Patients 1 and 2 had been working as a cashier (patient 1 at a restaurant and patient 2 at a grocery store). Patient 4 had been working from home.