Table 2.

Impacts of CCR5Δ32 on Influenza virus infection.

Population	Sample	Main findings	References
Canadian	20 individuals infected with 2009 pandemic H1N1	The CCR5Δ32 allele was considered a risk factor for severe infection among Caucasian individuals	Keynan et al. (2010)
Spanish	1 fatal case and 1 mild disease case (2009 pandemic H1N1)	The patient who died from the infection had CCR5Δ32 homozygous genotype	Rodriguez et al. (2013)
Mostly European	29 individuals (27 Italian; 1 Spanish; 1 Chinese) infected with 2009 pandemic H1N1	No association between the CCR5Δ32 and H1N1 infection	Sironi et al. (2014)
Spanish	171 individuals infected with 2009 pandemic H1N1	The CCR5Δ32 was associated with increased risk for fatal outcome	Falcon et al. (2015)
Brazilian	156 infected/hospitalized individuals; 174 infected (mild symptoms) but non-hospitalized individuals (2009 pandemic Influenza A H1N1)	No association between the CCR5Δ32 and H1N1 infection severity	Maestri et al. (2015)
Brazilian	153 influenza-like illness cases; 173 severe acute respiratory infection cases; 106 fatal cases (2009 pandemic H1N1)	No association between the CCR5Δ32 and H1N1 infection severity or mortality	Matos et al. (2019)