Table 3.
Impacts of CCR5Δ32 on Human papillomavirus (HPV) infection.
Population | Sample | Main findings | References |
---|---|---|---|
Swedish | 126 HPV-infected individuals; 173 non-infected individuals | CCR5Δ32 homozygous genotype was associated with increased risk of HPV infection | Zheng et al. (2006) |
Brazilian | 74 HPV-infected individuals; 43 non-infected individuals | No association between CCR5Δ32 and HPV infection; No association between CCR5Δ32 and HPV-related cancer | Suzuki et al. (2008) |
Brazilian | 139 HPV-infected individuals with cervical intraepithelial neoplasia or cervical cancer; 151 HPV-infected individuals without cervical lesions | No association between CCR5Δ32 and HPV-related lesions; No association between CCR5Δ32 and HPV genotypes | Santos et al. (2016) |
Brazilian | 164 HPV-infected individuals; 185 non-infected individuals | No statistically significant effect of CCR5Δ32 on susceptibility to HPV infection or HPV-related cervical lesions (low‐grade squamous intraepithelial lesion or high‐grade squamous intraepithelial lesion) | Mangieri et al. (2019) |
Lithuanian | 49 laryngeal squamous cell carcinoma patients (21 HPV-infected patients and 28 non-infected patients) | No statistically significant effect of CCR5Δ32 on susceptibility to HPV infection, clinical-pathological characteristics or surviving rates | Stumbrytė-Kaminskienė et al. (2020) |