Skip to main content
. 2020 May 30;286:198040. doi: 10.1016/j.virusres.2020.198040

Table 3.

Impacts of CCR5Δ32 on Human papillomavirus (HPV) infection.

Population Sample Main findings References
Swedish 126 HPV-infected individuals; 173 non-infected individuals CCR5Δ32 homozygous genotype was associated with increased risk of HPV infection Zheng et al. (2006)
Brazilian 74 HPV-infected individuals; 43 non-infected individuals No association between CCR5Δ32 and HPV infection; No association between CCR5Δ32 and HPV-related cancer Suzuki et al. (2008)
Brazilian 139 HPV-infected individuals with cervical intraepithelial neoplasia or cervical cancer; 151 HPV-infected individuals without cervical lesions No association between CCR5Δ32 and HPV-related lesions; No association between CCR5Δ32 and HPV genotypes Santos et al. (2016)
Brazilian 164 HPV-infected individuals; 185 non-infected individuals No statistically significant effect of CCR5Δ32 on susceptibility to HPV infection or HPV-related cervical lesions (low‐grade squamous intraepithelial lesion or high‐grade squamous intraepithelial lesion) Mangieri et al. (2019)
Lithuanian 49 laryngeal squamous cell carcinoma patients (21 HPV-infected patients and 28 non-infected patients) No statistically significant effect of CCR5Δ32 on susceptibility to HPV infection, clinical-pathological characteristics or surviving rates Stumbrytė-Kaminskienė et al. (2020)