Figure 2.

LDR Potentially Induces a Radiation-Associated Cellular Immunogenicity in the Virus-Infected Lung Tissue Which Attracts Immune Cells to the Infected Area

Radiation-induced immunogenicity of tumor cells has been well demonstrated by enhanced immune cell infiltration into the solid tumors via radiation-enhanced antigen transfer by immune cells. It is thus assumed that LDR-treated lung tissue with virus infection may generate potential specific immunogenicity capable of attracting the circulating immune cells to the infected area to reduce the virus loading and the CS. The postulated specific antigens induced by different doses of radiation in the infected lung tissue are to be identified with the soon available animal models with the SARS-CoV-2-mediated ARDS.