Figure 3.

Eliminating the In Situ Overactive Cytokine-Releasing Immune Cells by HDR to Reduce the Severity of CS

HDR-mediated immune suppression via the direct cytotoxicity on active immune cells may serve as an applicable tool in eliminating the local in situ overactive cytokine-releasing cells to reduce CS. Due to a relatively high radiosensitivity of lymphocytes, HDR may effectively suppress the cytokine-releasing immune cells and endothelial cells in the infected lung tissue. Thus, a treatment with HDR within the lung tolerable radiation doses may serve as a choice to instantly suppress CS for relieving the severity of ARDS by removing the cytokine-releasing cells.