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. 2020 May 30;10(7):1175–1191. doi: 10.1016/j.apsb.2020.05.009

Figure 3.

Figure 3

Airway T cells are protective against SARS-CoV challenge. (A) Survival rate of SARS-CoV infected mice after depletion of airway CD4+ T cells. n = 5, rIgG i.n.; n = 24, aCD4 i.n. (B) Virus titers of SARS-CoV infected mice after depletion of airway CD4+ T cells. Titers are expressed as PFU/g tissue. n = 3 mice/group/time point. *P < 0.05. Data are representative of two independent experiments. (C) Survival rate of SARS-CoV infected mice after depletion of airway CD8+ T cells. n = 5, rIgG i.p.; n = 7, aCD8 i.p. (D) Virus titers of SARS-CoV infected mice after depletion of airway CD8+ T cells. n = 3 mice/group/time point. *P < 0.05. Data are representative of two independent experiments. The figure was adapted with permission from Ref. 45. Copyright © 2016 Elsevier.